Contact
gasautto@uga.edu
706-542-8468
Room 1513, 501 D.W. Brooks Drive Athens, GA 30602
Education
BS, (2006), Medical Biotechnology, University of Milan
MS, (2008), Molecular and Cellular Medical Biotechnology, Vita-Salute San Raffaele University of Milan
PhD, (2012), Molecular Medicine, Vita-Salute San Raffaele University of Milan
Qualified as a Professional Biologist, (2015), University of Insubria of Varese
Affiliation
Member of the Editorial Board for Journal of Immunological Sciences, Current Trends in Vaccines and Vaccinology and Journal of Immunology Research.
Guest Editor for Frontiers in Immunology
Research Interest
Dr. Sautto's research is focused on the selection, cloning, characterization and engineering of monoclonal antibodies (mAbs), especially of human origin, and directed against infectious agents. In particular, the potential of these mAbs is investigated as possible drugs, able to directly neutralize infectious pathogens, or as indirect molecules to be exploited for the development of prophylactic approaches. Moreover, their possible engineering in order to improve (i.e. their binding or stability characteristics) or gain new functions (such as in the case of chimeric antigen receptors, CARs), represents a promising and alternative approach for difficult-to-eradicate infectious pathogens.
Recent Publications
Sautto GA, Kirchenbaum GA, Abreu RB, Ecker JW, Pierce SR, Kleanthous H, Ross TM. A Computationally Optimized Broadly Reactive Antigen Subtype-Specific Influenza Vaccine Strategy Elicits Unique Potent Broadly Neutralizing Antibodies against Hemagglutinin. 2020. J. Immunol. 204(2):375-385.
Abreu RB, Kirchenbaum GA, Clutter EF, Sautto GA, Ross TM. Pre-existing subtype immunodominance shapes memory B cell recall response to influenza vaccination. 2019. JCI Insight. pii: 132155
Sautto GA, Ross TM. Hemagglutinin consensus-based prophylactic approaches to overcome influenza virus diversity. 2019. Vet Ital. 55(3):195-201.
Sautto GA, Kirchenbaum GA, Diotti RA, Criscuolo E, Ferrara F. Next Generation Vaccines for Infectious Diseases. 2019. J Immunol Res. 2019:5890962.